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NOW Supplements Saccharomyces Boulardii
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.9
USERS' SCORE
Good
Based on 42 Reviews
8.9
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Saccharomyces boulardii (10 Billion CFU)(Saccharomyces cerevisiae var. boulardii I-3799)
1,000 mg
**

Top Medical Research Studies

9
Probiotic improves MS symptoms
The effect of probiotic supplementation on the clinical and para-clinical findings of multiple sclerosis: a randomized clinical trial.
Relevant study on MS treatment
We focused on the effects of the probiotic Saccharomyces boulardii on Multiple Sclerosis (MS) patients, comparing its benefits to a placebo over four months.

Notably, we found that Saccharomyces boulardii significantly lowered inflammatory markers and improved overall antioxidant capacity. Participants also reported less pain and fatigue, alongside enhancements in their quality of life compared to those receiving the placebo.

This suggests that incorporating Saccharomyces boulardii might help alleviate some symptoms related to MS, offering a beneficial avenue for symptom management.
Read More
9
Saccharomyces boulardii prevents IgAN
Saccharomyces boulardii prevents oral-poliovirus vaccine-induced IgA nephropathy in mice.
Indicates probiotic's protective effects
We evaluated how Saccharomyces boulardii affects IgA nephropathy in mice, particularly after an oral poliovirus vaccine (OPV).

The mice were divided into four groups—some receiving the OPV alone, others along with S. boulardii, and a few with just S. boulardii or no treatment.

After six weeks, we found that only the mice receiving the OPV alone showed signs of IgA nephropathy, with increased levels of serum IgA and kidney abnormalities.

In contrast, those treated with S. boulardii or receiving no treatment had normal results.

These findings suggest that S. boulardii can effectively prevent vaccine-induced IgA nephropathy in experimental models.
Read More
8
Saccharomyces boulardii shows potential
Saccharomyces boulardii (CNCM I-745) alleviates collagen-induced arthritis by partially maintaining intestinal mucosal integrity through TLR2/MYD88/NF-κB pathway inhibition.
Relevant for gut inflammation studies
We investigated how Saccharomyces boulardii might help with inflammation in arthritis by focusing on its effects on gut health. Using a rat model of collagen-induced arthritis, we administered S. boulardii alongside Methotrexate for eight weeks.

Our findings highlighted S. boulardii's potential to positively influence gut bacteria, which could be crucial for inflammation management. While the results seem promising, further studies are needed to clearly establish its effectiveness in autoimmune conditions like arthritis.
Read More

Most Useful Reviews

9.5
Cleared acne effectively
This is something cool. I am 26 years old, and I have acne constantly. Every few days "a new one arrives". I have tried various treatments with a cosmetologist, dermatologist, and gynecologist, but all advised me to accept my skin as it is, suggesting it would clear up after 30-35 years. I ordered these capsules, and within three days, surprisingly, not a single new pimple appeared. It's been two weeks now, taking one capsule three times daily, and the result is a clear, even complexion. I noticed no side effects, and the capsules taste neutral. I genuinely hope my review helps you achieve similar results. Thank you!
Read More
9.5
Cleared acne effectively
I'm 26 years old and suffer from persistent acne. Every few days, a new blemish appears. I sought help from a beautician, dermatologist, and gynaecologist, but they all suggested I learn to live with it because it will likely resolve itself in a decade or so. I tried these capsules, and by the third day of usage, I noticed no new pimples. My PMS phase came and went without the usual breakout. For two weeks, I have been taking one capsule three times daily post-meals, resulting in clear skin without side effects. I hope this helps others as well!
Read More
8.3
Helpful for family
A good helper for those with gastrointestinal disorders, effective for the whole family.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7.9
  • All Researches
9
Probiotic improves MS symptoms
The effect of probiotic supplementation on the clinical and para-clinical findings of multiple sclerosis: a randomized clinical trial.
Relevant study on MS treatment
We focused on the effects of the probiotic Saccharomyces boulardii on Multiple Sclerosis (MS) patients, comparing its benefits to a placebo over four months.

Notably, we found that Saccharomyces boulardii significantly lowered inflammatory markers and improved overall antioxidant capacity. Participants also reported less pain and fatigue, alongside enhancements in their quality of life compared to those receiving the placebo.

This suggests that incorporating Saccharomyces boulardii might help alleviate some symptoms related to MS, offering a beneficial avenue for symptom management.
Read More
9
Saccharomyces boulardii prevents IgAN
Saccharomyces boulardii prevents oral-poliovirus vaccine-induced IgA nephropathy in mice.
Indicates probiotic's protective effects
We evaluated how Saccharomyces boulardii affects IgA nephropathy in mice, particularly after an oral poliovirus vaccine (OPV).

The mice were divided into four groups—some receiving the OPV alone, others along with S. boulardii, and a few with just S. boulardii or no treatment.

After six weeks, we found that only the mice receiving the OPV alone showed signs of IgA nephropathy, with increased levels of serum IgA and kidney abnormalities.

In contrast, those treated with S. boulardii or receiving no treatment had normal results.

These findings suggest that S. boulardii can effectively prevent vaccine-induced IgA nephropathy in experimental models.
Read More
9
Effective IgA nephropathy treatment method
Yeast Cell Wall-Mediated Ileal Targeted Delivery System for IgA Nepharopathy Therapy.
Highly relevant therapeutic breakthrough
We explored a novel oral drug delivery system designed specifically for treating IgA nephropathy, an autoimmune disorder. Using hydroxychloroquine and dexamethasone paired with yeast cell walls, we aimed for targeted delivery to the ileal region.

Our findings revealed that this system effectively reduced harmful IgA levels and improved kidney tissue health in test subjects. We also noted significant reductions in inflammatory markers, suggesting potential benefits in managing IgA nephropathy through this innovative approach.
Read More
9
Yeast polysaccharides may reduce inflammation
Structural specificities of cell surface β-glucan polysaccharides determine commensal yeast mediated immuno-modulatory activities.
Highly relevant to autoimmune treatment
We investigated the role of certain yeast polysaccharides in modulating immune responses related to autoimmune disorders. Our focus was on mannan/β-1,6-glucan-containing polysaccharides (MGCP), which showed strong anti-inflammatory properties.

MGCP prompted the development of regulatory T cells and reduced harmful immune responses in models of inflammatory diseases. While we saw promising results in laboratory settings, these findings emphasize the potential of using yeast-derived compounds for therapeutic approaches in treating autoimmune conditions.
Read More
9
Effective anti-BAMBI treatment in mice
Therapeutic Effects of Anti-Bone Morphogenetic Protein and Activin Membrane-Bound Inhibitor Treatment in Psoriasis and Arthritis.
High relevance for autoimmune therapy
We investigated the effects of a novel treatment targeting BAMBI, a protein involved in immune cell regulation, on autoimmune disorders like psoriasis and arthritis in mice. Through careful experimentation with control groups, we found that the anti-BAMBI antibody significantly increased protective Treg cells and reduced disease progression in various models. This treatment effectively prevented skin psoriasis and type II collagen-induced arthritis, hinting at new therapeutic possibilities for chronic inflammatory conditions driven by immune system dysfunction.
Read More

User Reviews

USERS' SCORE
Good
Based on 42 Reviews
8.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Cleared acne effectively
This is something cool. I am 26 years old, and I have acne constantly. Every few days "a new one arrives". I have tried various treatments with a cosmetologist, dermatologist, and gynecologist, but all advised me to accept my skin as it is, suggesting it would clear up after 30-35 years. I ordered these capsules, and within three days, surprisingly, not a single new pimple appeared. It's been two weeks now, taking one capsule three times daily, and the result is a clear, even complexion. I noticed no side effects, and the capsules taste neutral. I genuinely hope my review helps you achieve similar results. Thank you!
Read More
9.5
Cleared acne effectively
I'm 26 years old and suffer from persistent acne. Every few days, a new blemish appears. I sought help from a beautician, dermatologist, and gynaecologist, but they all suggested I learn to live with it because it will likely resolve itself in a decade or so. I tried these capsules, and by the third day of usage, I noticed no new pimples. My PMS phase came and went without the usual breakout. For two weeks, I have been taking one capsule three times daily post-meals, resulting in clear skin without side effects. I hope this helps others as well!
Read More
8.3
Helpful for family
A good helper for those with gastrointestinal disorders, effective for the whole family.
9.5
Stopped discomfort
These probiotics are excellent, alleviating numerous intestinal disorders. The pleasant taste has stopped the gut's discomfort, eliminating bloating and heartburn. The quality is decent, with live bacteria ensuring the microbiome remains stable. The capsules are easy to swallow, and my stool has softened, greatly reducing negative symptoms.
Read More
9.5
Inflammation reduction
Works remarkably! I took it as advised by my gastroenterologist instead of enterol and found it cheaper. It helps with my indigestion, especially in summer after fruits. When inflammation returned, this jar was a lifesaver; my symptoms improved significantly after starting it again.
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